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    • Stereochemistry
      "Molecules which closely resemble each other, but fail to be identical due to one difference in their structures can be designated as isomers. When isomers have same atom connectivity but differ in spatial orientation of their atoms (configuration), they are designated as stereoisomers. The phenomenon of existence of stereoisomers is called stereoisomerism"...
    • Chirality
      “Chirality is a property of an object which is non-superimposable on its mirror image. The e word chiral stems from the Greek word “cheir”, which means ‘handedness’. When an object cannot be superimposed on its mirror image, such a pair is referred to as chiral. It is just like the left and right hands. The two non-superimposable mirror-image twins of a chiral molecule is called enantiomers.”...
    • Analytical Chiral Separation
      "Chiral analysis refers to the quantification of individual component enantiomers of racemic drug substances or pharmaceutical compounds. Chiral analysis is usually performed with chiral separation methods where the enantiomers are separated on an analytical scale and simultaneously assayed for each enantiomer."...
    • Preparative Chiral Separation
      “Enantiomeric separation is a key step in the development of a new chiral drug. Preparative liquid chromatography (LC) continues to be the technique of choice either during the drug discovery process, to achieve a few milligrams, or to a scale-up during the clinical trial, needing kilograms of material. ”
    • Chiral Synthesis
      “Building molecules is a difficult art. Benjamin List and David MacMillan are awarded the Nobel Prize in Chemistry 2021 for their development of a precise new tool for molecular construction: organocatalysis. This has had a great impact on pharmaceutical research, and has made chemistry greener.”….
    • Chiral Materials
      “Chirality is fundamental to chemistry, molecular biology and photonics, but chirality itself is not often in the spotlight. Lewis E. MacKenzie and Patrycja Stachelek report on the 2021 Chiral Materials meeting, which explored how chirality manifests in functional materials and how it can lead to new technological applications”...
    • Regulatory Affairs
      “Governmental regulations emphasizing the need to monitor chirality in drug development have increased. The United States Food and Drug Administration issued guidelines and policies in 1992 concerning the development of chiral compounds.”...
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