Chiralpedia

Chiralpedia
Nobel Prize in Chemistry 2021 awarded to Benjamin List and David MacMillan "for the development of asymmetric organocatalysis"
Nobel Prize in Chemistry 2021 awarded to Benjamin List and David MacMillan "for the development of asymmetric organocatalysis"
Nobel Prize in Chemistry 2021 awarded to Benjamin List and David MacMillan "for the development of asymmetric organocatalysis"
Nobel Prize in Chemistry 2021 awarded to Benjamin List and David MacMillan "for the development of asymmetric organocatalysis"
Nobel Prize in Chemistry 2021 awarded to Benjamin List and David MacMillan "for the development of asymmetric organocatalysis"

Chirality

Origin

"From atoms to human beings, nature is asymmetric with respect to chirality, or left- and right-handedness. Clues are beginning to emerge that connect chirality on different levels" ...

"All life on Earth is made of molecules that twist in the same direction. New research reveals that this may not always have been so" ...

"The mirror-image asymmetry of life is one of the biggest mysteries in biology" ...


Read more @ the following articles.

Drug Chirality

"Many medicinal agents important to life are combinations of mirror-image twins. Despite the close resemblance of such twins, the differences in their biological properties can be profound. In other words the component enantiomers of a racemic chiral drug may differ wildly in their pharmacokinetic, pharmacodynamic profile. The tragedy of thalidomide illustrates the potential for extreme consequences"...

Read more @ Wikipedia article links.


Links to some more publications in the area of drug chirality are given below. These articles and references therein might be of interest to readers.