Chiralpedia - Online resource for Chiral Science

<𝐓𝐡𝐞 𝐑𝐞𝐠𝐮𝐥𝐚𝐭𝐨𝐫𝐲 𝐉𝐨𝐮𝐫𝐧𝐞𝐲 𝐨𝐟 𝐂𝐡𝐢𝐫𝐚𝐥 𝐃𝐫𝐮𝐠𝐬> - Click to View

<The Regulatory Journey of Chiral Drugs> - Episode 1: When Mirror Images Mattered: A Historical Prelude to Chiral Drug Regulation

<The Regulatory Journey of Chiral Drugs> - Episode 2: The Great Shift: How the 1990s Redefined Stereochemical Standards

<The Regulatory Journey of Chiral Drugs> - Episode 3:Beyond Borders: Comparing How Global Agencies Regulate Chiral Drugs

<𝐓𝐡𝐞 𝐑𝐞𝐠𝐮𝐥𝐚𝐭𝐨𝐫𝐲 𝐉𝐨𝐮𝐫𝐧𝐞𝐲 𝐨𝐟 𝐂𝐡𝐢𝐫𝐚𝐥 𝐃𝐫𝐮𝐠𝐬> - Click to View

<The Regulatory Journey of Chiral Drugs> - Episode 1: When Mirror Images Mattered: A Historical Prelude to Chiral Drug Regulation

<The Regulatory Journey of Chiral Drugs> - Episode 2: The Great Shift: How the 1990s Redefined Stereochemical Standards

<The Regulatory Journey of Chiral Drugs> - Episode 3:Beyond Borders: Comparing How Global Agencies Regulate Chiral Drugs

News

NASA scientists want to solve a mystery: Why did life "turn left?"
https://www.yahoo.com/lifestyle/nasa-scientists-want-solve-mystery-110000851.html?guccounter=1 News Release: February 02, 2025

Debunked dogma: disordered proteins disregard ligands’ chirality
https://www.chemistryworld.com/news/debunked-dogma-disordered-proteins-disregard-ligands-chirality/4020682.article News Release: December 18, 2024
Confronting risks of mirror life | Science
https://www.science.org/doi/10.1126/science.ads9158

eLetter
https://www.science.org/doi/10.1126/science.ads9158#elettersSection News Release: December 12, 2024
The Cosmic Coin Toss: How Chirality Shaped Life’s Genetic Code
https://scitechdaily.com/the-cosmic-coin-toss-how-chirality-shaped-lifes-genetic-code/ News Release: December 2, 2024
A Breakthrough in Chiral Capsule Tools for Advanced Optical Technologies
https://www.isct.ac.jp/en/news/e1gewmolowsv News Release: October 7, 2024
Hidden Patterns Show Nobel Prize Science Trends
https://www.scientificamerican.com/article/hidden-patterns-show-nobel-prize-science-trends/ News Release: September 17, 2024
'Fussy' molecules prefer one direction over the other, chiral copolymer study finds
https://phys.org/news/2024-09-fussy-molecules-chiral-copolymer.html News Release: September 12, 2024
A Breakthrough in Chiral Molecule Research Opens New Horizons for Science
https://www.fhi.mpg.de/1600933/2024-08-29-Chiral-Molecule-Research News Release: August 29, 2024
New 'chiral vortex' of light allows chemists to 'see' molecules through the mirror
https://phys.org/news/2024-08-chiral-vortex-chemists-molecules-mirror.html News Release: August 23, 2024
Breakthrough in molecular control: New bioinspired double helix with switchable chirality
https://phys.org/news/2024-08-breakthrough-molecular-bioinspired-helix-switchable.amp News Release: August 23, 2024
New method for simultaneous high-resolution measurement of chiral molecules
https://phys.org/news/2024-07-method-simultaneous-high-resolution-chiral.html News Release: July 15, 2024
Inherent Chirality at work in Electrochemistry and Electroanalysis
https://sites.unimi.it/vince/index.php/chiral-electrochemistry/ News Release: 2024
Telling left from right: chirality detection faces up to its weaknesses
https://www.chemistryworld.com/news/telling-left-from-right-chirality-detection-faces-up-to-its-weaknesses/4019242.article News Release: 8 April 2024
First mirror-image cyclodextrins come together ‘like Lego’
https://www.chemistryworld.com/news/first-mirror-image-cyclodextrins-come-together-like-lego/4019263.article News Release: 05 April 2024
Why is DNA almost always a right-handed helix? Exploring the causes of chirality
https://phys.org/news/2024-03-dna-helix-exploring-chirality.html News Release: 22 March 2024
How molecular 'handedness' emerged in early biology
https://www.sciencedaily.com/releases/2024/02/240228115459.htm News Release: 28 February 2024
AI and Machine Learning Revolutionize Computational Chemistry, From Quantum Chemistry to machine learning and back
https://quantumzeitgeist.com/ai-and-machine-learning-revolutionize-computational-chemistry-from-quantum-chemistry-to-machine-learning-and-back/ News Release: 19 February 2024
Observing Chirality
https://entropix.co.uk/observing-chirality/ News Release: 6 February 2024
Researchers report successful synthesis of specific chiral molecules using rearrangements of simple hydrocarbons
https://phys.org/news/2024-01-successful-synthesis-specific-chiral-molecules.html News Release: 10 January 2024
Stripes in a flowing liquid crystal suggest a route to 'chiral' fluids
https://phys.org/news/2024-01-stripes-liquid-crystal-route-chiral.html#google_vignette News Release: 08 January 2024

Molecular handedness controls spin
https://cen.acs.org/materials/nanomaterials/Molecular-handedness-controls-spin/101/i35 News Release: October 19, 2023
Chiral detection of molecules gets a laser-driven boost
https://physicsworld.com/a/chiral-detection-of-molecules-gets-a-laser-driven-boost/ News Release: 03 October 2023
A new way to identify chiral molecules with light could vastly improve detection efficiency
https://phys.org/news/2023-08-chiral-molecules-vastly-efficiency.html News Release: 18 August 2023
Organocatalysis: Reflecting on Two Decades of Innovation
https://jakemp.com/en/insights/organocatalysis-reflecting-on-two-decades-of-innovation/ News Release: 7 July 2023
For chemists, the AI revolution has yet to happen
https://www.nature.com/articles/d41586-023-01612-x News Release: 17 May 2023
'Breakthrough’ could explain why life molecules are left- or right-handed
https://www.science.org/content/article/breakthrough-could-explain-why-life-molecules-are-left-or-right-handed News Release: 13 June 2023
"Mirror-Image" Molecules Open the Door to Better Cancer Treatments
https://scitechdaily.com/mirror-image-molecules-open-the-door-to-better-cancer-treatments/ SCRIPPS RESEARCH INSTITUTE MAY 2, 2023
'Dynamic bonds' reshape the rules of aromaticity and chirality
https://www.chemistryworld.com/news/dynamic-bonds-reshape-the-rules-of-aromaticity-and-chirality/4017189.article News Release: 24 March 2023
This new molecule owes its chirality to oxygen alone
https://cen.acs.org/synthesis/new-molecule-owes-chirality-oxygen/101/web/2023/03 News Release: 19 March 2023
Scientists interconvert mirror-image molecules
https://www.durham.ac.uk/news-events/latest-news/2023/03/scientists-interconvert-mirror-image-molecules/ News Release: 13 March 2023
’Photoredox catalysis goes asymmetric’: counterion strategy a breakthrough in reaction control
https://www.chemistryworld.com/news/photoredox-catalysis-goes-asymmetric-counterion-strategy-a-breakthrough-in-reaction-control/4016868.article News Release: 31 January 2023
Distinguishing between right and left with magnets
https://phys.org/news/2023-01-distinguishing-left-magnets.html News Release: 18 January 2023

Light can be used to control molecular handedness
https://phys.org/news/2022-12-molecular-handedness.html News Release: December 13, 2023
Taking inspiration from nature to make molecules like nature does
https://www.caltech.edu/about/news/taking-inspiration-from-nature-to-make-molecules-like-nature-does News Release: December 12 2022
Gigantic database of building blocks will help artificial intelligence uncover new organocatalysts
https://www.chemistryworld.com/news/gigantic-database-of-building-blocks-will-help-artificial-intelligence-uncover-new-organocatalysts/4016574.article News Release: November 21 2022
Researchers reveal structure and function of a molecular motor
https://phys.org/news/2022-08-reveal-function-molecular-motor.html News Release: 26 Aug 2022
Helical light tells chiral molecules apart
https://physicsworld.com/a/helical-light-tells-chiral-molecules-apart/ News Release: 05 Aug 2022
Many drugs have mirror image chemical structures – while one may be helpful, the other may be harmful
https://theconversation.com/many-drugs-have-mirror-image-chemical-structures-while-one-may-be-helpful-the-other-may-be-harmful-186975 News Release: 03 Aug 2022
Catalysis Is One of the Most Important Technologies for Mankind – And We’re Just Getting Started With It
https://www.lindau-nobel.org/blog-catalysis-is-one-of-the-most-important-technologies-for-mankind-and-were-just-getting-started-with-it/ News Release: 30 June 2022
The Key to Chirality
https://theanalyticalscientist.com/techniques-tools/the-key-to-chirality News Release: 10 May 2022
A nose for damaged plants and fake perfumes
https://www.mpg.de/18855876/chiral-signature-perfume-plant News Release: 25 June 2022
Spin-controlling materials team win prestigious Horizon Prize
https://www.imperial.ac.uk/news/236894/spin-controlling-materials-team-prestigious-horizon-prize/ News Release: 07 June 2022
Is there asymmetry in nature?
https://cosmosmagazine.com/science/biology/is-there-asymmetry-in-nature/ News Release: May 11, 2022
Metamaterial significantly enhances chiral nanoparticle signals
https://phys.org/news/2022-05-metamaterial-significantly-chiral-nanoparticle.html News Release: May 3, 2022
Life’s chemistry goes through the looking glass
https://www.chemistryworld.com/features/lifes-chemistry-goes-through-the-looking-glass/4015507.article News Release: May 3, 2022
Controlling chemical mirror images
https://phys.org/news/2022-04-chemical-mirror-images.html News Release: April 29, 2022
How asymmetry could make better vaccines
https://cosmosmagazine.com/science/chemistry/vaccine-chirality-asymmetry-adjuvant/ News Release: April 20, 2022
A biological motor that consumes chiral fuel drives rotation in one direction around a single covalent bond
https://phys.org/news/2022-04-biological-motor-consumes-chiral-fuel.html News Release: April 20, 2022
Chiral gold nanoparticles increase vaccine efficacy by more than 25%, study suggests
https://phys.org/news/2022-04-chiral-gold-nanoparticles-vaccine-efficacy.html News Release: April 18, 2022
Evolutionary scientists find symmetry in nature, and beauty in simplicity
https://www.fastcompany.com/90731192/evolutionary-scientists-find-symmetry-in-nature-and-beauty-in-simplicity News Release: March 14, 2022
Is there asymmetry in nature?
https://cosmosmagazine.com/science/biology/is-there-asymmetry-in-nature/ News Release: March 11, 2022
Changing the handedness of molecules
https://www.eurekalert.org/news-releases/946253 News Release: March 9, 2022
We exist thanks to chirality and the asymmetry of life
https://bigthink.com/13-8/chirality-asymmetry-life/ News Release: 23 Feb 2022
Symmetry is beautiful, but asymmetry is why the Universe and life exist
https://bigthink.com/13-8/matter-antimatter-asymmetry/ News Release: 09 Feb 2022
Cell Chirality Offers Clues to the Mystery of Body Asymmetry
https://www.the-scientist.com/cell-chirality-offers-clues-to-the-mystery-of-body-asymmetry-69584 News Release: 01 Feb 2022
Twisted light from semiconducting nanohelices could speed drug discovery
https://physicsworld.com/a/twisted-light-from-semiconducting-nanohelices-could-speed-drug-discovery/ News Release: 24 Jan 2022

News on chirality
https://www.chemeurope.com/en/news/topic/chirality/
Taking some of the guesswork out of drug discovery
https://news.mit.edu/2021/model-predicts-3d-molecule-drugs-1206 News Release: December 6, 2021
The Right Chemistry: Reflecting on mirror-image molecules
https://montrealgazette.com/opinion/columnists/the-right-chemistry-reflecting-on-mirror-image-molecules News Release: November 12, 2021
Nobel Prize for simple but brilliant discovery of asymmetric organocatalysis
https://journosdiary.com/2021/10/28/nobel-prize-for-simple-but-brilliant-discovery-of-asymmetric-organocatalysis/ News Release: October 28, 2021
How organocatalysis won the Nobel prize
https://www.chemistryworld.com/features/how-organocatalysis-won-the-nobel-prize/4014582.article News Release: October 15, 2021
Mirror's Image: Could a Simple Flip Produce a More Effective Ketamine-Based Antidepressant?
https://www.technologynetworks.com/neuroscience/blog/mirrors-image-could-a-simple-flip-produce-a-more-effective-ketamine-based-antidepressant-347554 News release: April 12, 2021
Breakthrough in organic chemistry: Asymmetric syntheses of useful, unique chiral compounds
https://phys.org/news/2021-02-breakthrough-chemistry-asymmetric-unique-chiral.html News Release: February 16, 2021
Diamond celebrates 10,000th paper – A breakthrough in chiral polymer thin films research
https://www.diamond.ac.uk/Home/News/LatestNews/2021/20-01-21.html News Release: January 1, 2021

New, ultrastable tetrahedral "chiral zinc" added to synthetic chemistry toolbox Catalyst with chirality at the zinc center could be useful for drug, electronic manufacturing
https://www.eurekalert.org/news-releases/494682 News Release: December 15, 2020
Nature through the looking glass
https://www.symmetrymagazine.org/article/nature-through-the-looking-glass?language_content_entity=und News Release: September 22, 2020
Discovery of naturally chiral surfaces for safer pharmaceuticals
https://engineering.cmu.edu/news-events/news/2020/08/07-chirality.html News Release: August 8, 2020
Researchers access both enantiomers by varying reaction time
https://phys.org/news/2020-06-access-enantiomers-varying-reaction.html News Release: June 30, 2020
Using magnets to separate chiral molecules
https://www.rsc.org/news-events/journals-highlights/2019/may/magnets-separate-chiral-molecules/
Scientists propose strategy for site-selective chiral drug synthesis in living systems
https://phys.org/news/2020-06-scientists-strategy-site-selective-chiral-drug.html News Release : June 26, 2020
Scientists eliminate drug side effects by manipulating molecular chirality
https://phys.org/news/2020-05-scientists-drug-side-effects-molecular.html News Release: May 19, 2020
Life's other mystery: Why biology's building blocks are so lop-sided
https://www.newscientist.com/article/mg24632780-700-lifes-other-mystery-why-biologys-building-blocks-are-so-lop-sided/ News Release: April 15, 2020
Mechanical chirality gives new shape to catalysis
https://cen.acs.org/synthesis/catalysis/Mechanical-chirality-gives-new-shape/98/i10 News Release : March 15, 2020
Research uncovers a new way of making chiral catalysts
https://www.eurekalert.org/news-releases/810744 News Release: March 9, 2020

Using corkscrew lasers to separate chiral molecules
https://phys.org/news/2019-12-corkscrew-lasers-chiral-molecules.html News Release: December 17, 2019
Observing changes in the chirality of molecules in real time
https://phys.org/news/2019-11-chirality-molecules-real.html News Release: November 14, 2019
Multi-state switchable stationary phase opens new doors in chiral separation
https://phys.org/news/2019-07-multi-state-switchable-stationary-phase-doors.html News Release: July 31, 2019
Magnets on hand for separating chiral crystals
https://www.chemistryworld.com/news/magnets-on-hand-for-separating-chiral-crystals/3010416.article News Release: May 1, 2019
Nat Cell Bio: “Mirror” Synthetic Biology Technology to Improve the Therapeutic Effect of Antibody Molecules
https://www.creative-biolabs.com/blog/index.php/nat-cell-bio-mirror-synthetic-biology-technology-to-improve-the-therapeutic-effect-of-antibody-molecules/ News Release: March 25, 2019
Chirality inversion in a helical molecule at controlled speeds
https://phys.org/news/2019-02-chirality-inversion-helical-molecule.html News Release: February 6, 2019
Chirality measurements speed up
https://physicsworld.com/a/chirality-measurements-speed-up/ News Release: January 21, 2019
Chiral curiosities
https://www.chemistryworld.com/opinion/chiral-curiosities/3009909.article News Release: January 9, 2019

Divide and conquer: A key to creating better medicines with fewer side effects
https://www.chemeurope.com/en/news/1155038/ News release: May 14, 2018
Magnetic fields could fish out enantiomers
https://cen.acs.org/analytical-chemistry/separations/Magnetic-fields-fish-enantiomers/96/i20 News release: May 11, 2018
A new toolset for studying chirality at the single molecule level
https://communities.springernature.com/posts/a-new-toolset-for-studying-chirality-at-the-single-molecule-level News release: June 20, 2018

The three pillars of asymmetric catalysis
https://remotecat.blogspot.com/2017/12/the-three-pillards-of-asymmetric.html News Release: December 03, 2017
Teaching Life a New Trick: Bacteria Make Boron-Carbon Bonds
https://sustainability.caltech.edu/sustainability-news/teaching-life-new-trick-bacteria-make-boron-carbon-bonds-80488 News Release: November 29, 2017
Chiral crabs
https://phys.org/news/2017-09-chiral-crabs.html News Release: September 22, 2017
New Porous Solids May Lead to Better Drugs
https://www.caltech.edu/about/news/new-porous-solids-may-lead-better-drugs-58429 News Release: May 01, 2017

Right Hand, Left Hand, Either Hand
https://www.science.org/content/blog-post/right-hand-left-hand-either-hand News Release: September 28, 2016
Must the Molecules of Life Always be Left-Handed or Right-Handed?
https://www.smithsonianmag.com/space/must-all-molecules-life-be-left-handed-or-right-handed-180959956/ News Release: July 28, 2016
'Handed' molecule found in space - what's the big deal?
https://cosmosmagazine.com/space/handed-molecule-found-in-space-whats-the-big-deal/ News Release: June 15, 2016

The origin of homochirality
https://www.chemistryworld.com/features/the-origin-of-homochirality/9073.article News Release : October 26, 2015
Sniffing Out Chirality
https://theanalyticalscientist.com/fields-applications/sniffing-out-chirality News Release : Februray 20, 2015

New Twist Found in the Story of Life’s Start
https://www.quantamagazine.org/chiral-key-found-to-origin-of-life-20141126 News Release : November 26, 2014
Synthetic Biology: The Next Frontier in Chiral Chemistry for API Synthesis
https://www.pharmtech.com/view/synthetic-biology-next-frontier-chiral-chemistry-api-synthesis News Release: 2 March 2024

Snapshots differentiate molecules from their mirror image
https://phys.org/news/2013-11-snapshots-differentiate-molecules-mirror-image.html News Release: November 29, 2013
Microwaves show their hand
https://www.chemistryworld.com/news/microwaves-show-their-hand/6193.article News Release: May 24, 2013

Magneto-Chiral Dichroism of Organic Compounds
https://doi.org/10.1002/anie.201101809 News Release : July 27, 2011

Molecular control earns Nobel
http://news.bbc.co.uk/1/hi/sci/tech/1590873.stm News Release : October 10, 2001
Chemical 'Handedness' Garners Big Applause
https://www.science.org/content/article/chemical-handedness-garners-big-applause News Release : October 10, 2001