In the 1940s and early 1950s, pregnant women throughout the world who experienced morning sickness and other anxieties associated with the first term of pregnancy were given barbiturate sedatives for relief. The issue with these barbiturates, like most sedatives, was the fact that they were highly toxic in large doses. In 1957, Chemie Grunenthal of …
In nature, most chiral molecules only appear in one specific enantiomeric form. [Read more @ the blog – “The handed world“, https://chiralpedia.com/blog/the-handed-world/]. Moreover, the handedness of the enantiomer can have a powerful effect on how that molecule behaves. The chiral difference between two molecules often plays a huge role in pharmacology and physiology, even though …
This blog is about the behavior of chiral twins in bio-environment. Dwells briefly on chiral discrimination and chiral pharmacology.
This post is to highlight the prominence of chirality in natural products, pharmaceuticals and drug research.