#chiral_chromatography

Chiral chromatography

What is chiral chromatography? Chiral chromatography is now widely understood and applied in daily life. The correct phrase, however, is “enantioselective chromatography”. Chiral chromatography has developed into the most popular method for enantiomeric purity assessment and pure enantiomer separation, both on an analytical and preparative scale. The initial step in any investigation into enantioselective synthesis …

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Separating mirrored molecules

In nature, most chiral molecules only appear in one specific enantiomeric form. [Read more @ the blog – “The handed world“, https://chiralpedia.com/blog/the-handed-world/]. Moreover, the handedness of the enantiomer can have a powerful effect on how that molecule behaves. The chiral difference between two molecules often plays a huge role in pharmacology and physiology, even though …

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Recent Comments

Dr. Sivakumar Thanikachalam on Episode 4: Fungicides and StereochemistryMay 30, 2026
An excellent and insightful article highlighting how stereochemistry influences fungicide efficacy, environmental fate, and sustainability in modern agriculture. Appreciation to…
Dr. Sivakumar Thanikachalam on Episode 3: Herbicides and the Role of ChiralityMay 27, 2026
An excellent and well-articulated article highlighting the significance of chirality in herbicides with impressive scientific depth and practical relevance. Truly…
Valliappan Kannappan on Case Study Through the Chiralpedia Lens: tert-Butanesulfinamide — The Sulfur-Centered Chiral Tool That Changed Drug SynthesisMarch 25, 2026
Thank you for your kind words. It was a privilege to highlight Prof. Ellman’s remarkable contributions—truly a legacy that continues…
Dr. Sivakumar Thanikachalam on Case Study Through the Chiralpedia Lens: tert-Butanesulfinamide — The Sulfur-Centered Chiral Tool That Changed Drug SynthesisMarch 25, 2026
A wonderful and insightful write-up! My sincere appreciation to Dr. Valliappan for elegantly highlighting the noble and impactful research of…
Valliappan Kannappan on Episode 1: The Promise and the Paradox: AI That Miss the MirrorFebruary 8, 2026
I share your optimism — refinement will come. But improvement isn’t automatic. If the data and benchmarks remain stereo-sloppy, models…
Valliappan Kannappan on 🪞Why the Language of Chirality Must Evolve: When Molecules Speak in 3D and Models Listen in 2D🤖February 7, 2026
Absolutely — thank you for that thoughtful insight. Chiral literacy isn’t a computational luxury; it’s a scientific necessity. If our…
Shriram on 🪞Why the Language of Chirality Must Evolve: When Molecules Speak in 3D and Models Listen in 2D🤖February 7, 2026
This is a vital topic very well articulated by authors. The importance of this chiral literacy needs to be instilled…
Paul Spurr on Episode 1: The Promise and the Paradox: AI That Miss the MirrorDecember 26, 2025
Presumably the situation will improve & this inconsistency will inevitably be overcome with further development & associated refinement.
Asian Chemical Forum on P4. Catalysts of Change: Advancements in Asymmetric SynthesisJune 30, 2025
Fascinating read on asymmetric synthesis breakthroughs! The article brilliantly showcases how P4 catalysts are revolutionizing enantioselective reactions – a game-changer…
Srinivasan Ganapathy on Chiral chromatographyDecember 27, 2024
Good article. Please do take seminar for chiral chromatography.