Part 8: Stereochemistry in Biologics and Natural Products
“Nature’s stereochemists – chirality in biologics, peptides, and natural products” Introduction Stereochemistry is inherent in biological macromolecules and natural products. This part explores chirality beyond small synthetic drugs – specifically, in biologics (peptides, proteins, nucleic acids) and in natural product-derived drugs. We examine how nature’s biosynthetic machinery imparts stereochemistry with high fidelity (e.g., enzymes produce …
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