Levobupivacaine
Bupivacaine is a long acting local anesthetic in use for many years as a spinal/epidural anesthetic for childbirth and orthopedic procedures, such as hip replacement. It is marketed by AstraZeneca under the trade name Chirocaine. It acts by blocking Na+ channels and also has actions on the heart, which restrict its use by intravenous injection for regional anesthesia. Chirality and Biological activity Bupivacaine is a racemic drug. This an example where the distomer shows toxic effect …