Quadrant Model (Hydrogenation)
Empirical model mapping steric quadrants around metal–ligand catalysts to predict facial selectivity.
Context: Used with Rh-DuPHOS, BINAP-Ru systems for enantioface control.
Example: Asymmetric hydrogenation of dehydroamino acids.
Related Terms: Bite Angle, Chiral Ligand.
Reference: Knowles/Halpern analyses (1970s–1990s).