The Hidden Chirality in Drug Metabolites: A metabolic blind spot
“Chirality isn’t hidden — we just stopped looking closely enough” The Unseen Journey After the Dose: Sometimes, the real chiral story begins after the dose 💊 When a patient swallows a drug, the journey is far from over. The compound meets a series of enzymes — oxidases, reductases, transferases — each capable of transforming it into one or more metabolites. We often assume these are simply inactive breakdown products, but chemistry rarely plays it that …
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