Erythro- and Threo- prefixes: the (same-) or (opposite-) side?
“Chloramphenicol possesses two chiral carbon atoms in the acylamidopropanediol chain. Biological activity resides almost exclusively in the D-threo-, isomer: the L-threo–and the D– and L-erythro– isomers are virtually inactive.” – – – from “Wilson and Gisvold’s Textbook of organic medicinal and pharmaceutical chemistry”. In the name “D-threo– and L-threo-Chloramphenicol”, what does the prefix threo– and erythro– in the nomenclature mean? How do we translate the name to structure? This blog is basically to understand and …
Erythro- and Threo- prefixes: the (same-) or (opposite-) side? Read More »